BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
SLC1A3
EAAT1, GLAST, GLAST-1, GluT-1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
GO Process (21)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- D-aspartate import [ISO]
- L-glutamate import [ISO]
- L-glutamate transmembrane transport [IDA, IMP, ISO, TAS]
- L-glutamate transport [IDA, IMP, ISO]
- auditory behavior [ISO]
- cell morphogenesis involved in neuron differentiation [ISO]
- cranial nerve development [ISO]
- gamma-aminobutyric acid biosynthetic process [ISO]
- glutamate biosynthetic process [ISO]
- glutamate metabolic process [ISO]
- malate-aspartate shuttle [IDA]
- neuromuscular process controlling balance [ISO]
- neurotransmitter transport [TAS]
- positive regulation of synaptic transmission [ISO]
- response to antibiotic [ISO]
- response to drug [ISO]
- response to inorganic substance [IDA]
- response to light stimulus [ISO]
- response to wounding [ISO]
- sensory perception of sound [ISO]
- sodium ion transmembrane transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID