BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
CX3CL1
Cx3c, Scyd1
chemokine (C-X3-C motif) ligand 1
GO Process (25)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
- aging [IEP]
- angiogenesis involved in wound healing [ISO]
- cell chemotaxis [IDA]
- chemotaxis [IDA, ISO]
- cytokine-mediated signaling pathway [ISO]
- lymphocyte chemotaxis [ISO]
- macrophage chemotaxis [ISO]
- microglial cell activation [IDA]
- negative regulation of cytokine secretion [IMP]
- negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [ISO]
- negative regulation of vasoconstriction [IDA]
- neutrophil chemotaxis [ISO]
- platelet activation [IMP]
- positive regulation of angiogenesis [ISO]
- positive regulation of calcium-independent cell-cell adhesion [ISO]
- positive regulation of cell adhesion [IDA]
- positive regulation of cell migration [IDA]
- positive regulation of inflammatory response [ISO]
- positive regulation of macrophage chemotaxis [IMP]
- positive regulation of neuroblast proliferation [IDA]
- positive regulation of smooth muscle cell proliferation [IDA]
- positive regulation of transforming growth factor beta1 production [ISO]
- regulation of inhibitory postsynaptic membrane potential [IMP]
- response to hypoxia [IEP]
- wound healing [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID