BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
BAG6
Bat3
BCL2-associated athanogene 6
GO Process (16)
GO Function (5)
GO Component (7)
Gene Ontology Biological Process
- brain development [ISO, ISS]
- internal peptidyl-lysine acetylation [ISO, ISS]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [ISO, ISS]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [ISO, ISS]
- kidney development [ISO, ISS]
- lung development [ISO, ISS]
- negative regulation of apoptotic process [ISO]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [ISO, ISS]
- negative regulation of proteolysis [ISO, ISS]
- protein stabilization [ISO, ISS]
- regulation of apoptotic process [ISO]
- regulation of cell proliferation [IEP]
- spermatogenesis [ISO, ISS]
- synaptonemal complex assembly [ISO, ISS]
- tail-anchored membrane protein insertion into ER membrane [ISO, ISS]
- ubiquitin-dependent protein catabolic process [ISO, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID