BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
MAPK9
SAPK
mitogen-activated protein kinase 9
GO Process (34)
GO Function (6)
GO Component (4)
Gene Ontology Biological Process
- JNK cascade [IDA, ISO]
- JUN phosphorylation [IMP]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- cellular response to UV [IMP]
- cellular response to growth factor stimulus [IEP]
- cellular response to interleukin-1 [IEP]
- cellular response to lipopolysaccharide [IEP]
- cellular response to tumor necrosis factor [IEP]
- central nervous system development [IEP]
- neuron projection development [IMP]
- positive regulation of apoptotic process [IMP]
- positive regulation of apoptotic signaling pathway [ISO]
- positive regulation of cell morphogenesis involved in differentiation [IMP]
- positive regulation of chemokine production [IMP]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- positive regulation of gene expression [ISO]
- positive regulation of macrophage derived foam cell differentiation [ISO]
- positive regulation of nitric oxide biosynthetic process [IMP]
- positive regulation of nitric-oxide synthase biosynthetic process [IMP]
- positive regulation of prostaglandin biosynthetic process [IMP]
- positive regulation of prostaglandin secretion [IMP]
- positive regulation of protein phosphorylation [IMP]
- positive regulation of transcription, DNA-templated [IMP]
- protein phosphorylation [IDA]
- protein targeting to mitochondrion [IEP]
- regulation of JNK cascade [IMP]
- regulation of protein ubiquitination [IMP]
- release of cytochrome c from mitochondria [IMP]
- response to amine [IEP]
- response to cadmium ion [ISO]
- response to drug [IMP]
- response to mechanical stimulus [IEP]
- response to organic substance [IEP]
- response to toxic substance [IEP]
Gene Ontology Molecular Function
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID