BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
POR
CYPOR
P450 (cytochrome) oxidoreductase
GO Process (24)
GO Function (12)
GO Component (4)
Gene Ontology Biological Process
- carnitine metabolic process [IEP]
- cellular organofluorine metabolic process [ISO]
- cellular response to follicle-stimulating hormone stimulus [IEP]
- cellular response to gonadotropin stimulus [IEP]
- cellular response to peptide hormone stimulus [IEP]
- demethylation [IDA]
- fatty acid oxidation [IDA]
- flavonoid metabolic process [IEP]
- internal peptidyl-lysine acetylation [IDA]
- negative regulation of apoptotic process [IMP]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- negative regulation of lipase activity [IDA]
- nitrate catabolic process [IDA]
- nitric oxide catabolic process [IDA, IMP]
- oxidation-reduction process [IDA, ISO]
- positive regulation of cholesterol biosynthetic process [IMP]
- positive regulation of chondrocyte differentiation [IMP]
- positive regulation of monooxygenase activity [ISO]
- positive regulation of smoothened signaling pathway [IMP]
- positive regulation of steroid hormone biosynthetic process [IDA]
- regulation of cholesterol metabolic process [IMP]
- regulation of growth plate cartilage chondrocyte proliferation [IMP]
- response to drug [IEP]
- response to nutrient [IEP]
Gene Ontology Molecular Function- FMN binding [IMP]
- NADP binding [IDA, IMP]
- NADPH-hemoprotein reductase activity [IDA, IMP, ISO]
- cytochrome-b5 reductase activity, acting on NAD(P)H [IDA]
- electron carrier activity [IDA]
- enzyme binding [IDA, IMP, IPI]
- flavin adenine dinucleotide binding [IMP]
- hydrolase activity [IDA]
- iron-cytochrome-c reductase activity [IDA]
- nitric oxide dioxygenase activity [IDA]
- oxidoreductase activity [ISO]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [IBA]
- FMN binding [IMP]
- NADP binding [IDA, IMP]
- NADPH-hemoprotein reductase activity [IDA, IMP, ISO]
- cytochrome-b5 reductase activity, acting on NAD(P)H [IDA]
- electron carrier activity [IDA]
- enzyme binding [IDA, IMP, IPI]
- flavin adenine dinucleotide binding [IMP]
- hydrolase activity [IDA]
- iron-cytochrome-c reductase activity [IDA]
- nitric oxide dioxygenase activity [IDA]
- oxidoreductase activity [ISO]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [IBA]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID