BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
NME2
NDKB, nm23-2, p18-12d
NME/NM23 nucleoside diphosphate kinase 2
GO Process (20)
GO Function (6)
GO Component (12)
Gene Ontology Biological Process
- CTP biosynthetic process [IDA]
- GTP biosynthetic process [IDA]
- UTP biosynthetic process [IDA]
- cellular response to fatty acid [IEP]
- cellular response to glucose stimulus [IEP]
- cellular response to oxidative stress [IEP]
- integrin-mediated signaling pathway [ISO, ISS]
- negative regulation of apoptotic process [ISO, ISS]
- negative regulation of myeloid leukocyte differentiation [IDA]
- nucleoside diphosphate phosphorylation [IDA]
- nucleoside triphosphate biosynthetic process [ISO]
- positive regulation of cAMP biosynthetic process [IMP]
- positive regulation of epithelial cell proliferation [ISO, ISS]
- positive regulation of keratinocyte differentiation [ISO, ISS]
- positive regulation of neuron projection development [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISO, ISS]
- protein autophosphorylation [IDA]
- protein oligomerization [IDA]
- regulation of epidermis development [ISO, ISS]
- response to growth hormone [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID