BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PALM
paralemmin
GO Process (11)
GO Function (1)
GO Component (15)
Gene Ontology Biological Process
- cellular response to electrical stimulus [ISO]
- cytoskeleton organization [ISO]
- negative regulation of adenylate cyclase activity [ISO]
- negative regulation of cAMP biosynthetic process [ISO]
- negative regulation of dopamine receptor signaling pathway [ISO]
- positive regulation of dendritic spine development [ISO]
- positive regulation of filopodium assembly [ISO]
- protein localization [ISO]
- protein targeting to plasma membrane [ISO]
- regulation of cell shape [ISO]
- synapse maturation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apicolateral plasma membrane [IDA]
- axon [IDA]
- basolateral plasma membrane [IDA]
- cytoplasm [ISO]
- cytoplasmic side of plasma membrane [TAS]
- dendrite membrane [IDA]
- dendritic spine membrane [IDA]
- filopodium [ISO]
- filopodium membrane [ISO]
- intracellular membrane-bounded organelle [ISO]
- neuron spine [ISO]
- neuronal postsynaptic density [ISO]
- nucleoplasm [ISO]
- nucleus [ISO]
- plasma membrane [IDA, ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID