BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PRDX1
Hbp23
peroxiredoxin 1
GO Process (10)
GO Function (7)
GO Component (11)
Gene Ontology Biological Process
- cell proliferation [ISO]
- erythrocyte homeostasis [ISO]
- hydrogen peroxide catabolic process [ISO]
- natural killer cell mediated cytotoxicity [ISO]
- regulation of NF-kappaB import into nucleus [ISO]
- regulation of stress-activated MAPK cascade [ISO]
- removal of superoxide radicals [ISO]
- response to oxidative stress [IDA, ISO]
- response to reactive oxygen species [ISO]
- retina homeostasis [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID