BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
ATP2B2
PMCA2
ATPase, Ca++ transporting, plasma membrane 2
GO Process (33)
GO Function (9)
GO Component (12)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- auditory receptor cell stereocilium organization [ISO]
- brain development [IEP]
- cGMP metabolic process [ISO]
- calcium ion export [IMP]
- calcium ion transmembrane transport [ISO, ISS]
- calcium ion transport [ISO]
- cell morphogenesis [ISO]
- cellular calcium ion homeostasis [ISO]
- cerebellar Purkinje cell differentiation [ISO]
- cerebellar Purkinje cell layer morphogenesis [ISO]
- cerebellar granule cell differentiation [ISO]
- cerebellum development [ISO]
- cochlea development [ISO]
- cytosolic calcium ion homeostasis [ISO]
- detection of mechanical stimulus involved in sensory perception of sound [ISO]
- inner ear development [ISO]
- inner ear morphogenesis [ISO]
- inner ear receptor cell differentiation [ISO]
- lactation [ISO]
- locomotion [ISO]
- locomotory behavior [ISO]
- neural retina development [IEP]
- neuromuscular process controlling balance [ISO]
- neuron differentiation [ISO, ISS]
- organelle organization [ISO]
- otolith mineralization [ISO]
- positive regulation of calcium ion transport [ISO]
- regulation of cell size [ISO]
- regulation of synaptic plasticity [ISO]
- sensory perception of sound [ISO, ISS]
- serotonin metabolic process [ISO]
- synapse organization [ISO]
Gene Ontology Molecular Function- ATP binding [IDA, ISO, ISS]
- PDZ domain binding [IPI, ISO, ISS]
- acetylcholine receptor binding [IDA]
- calcium ion binding [ISO, ISS]
- calcium-dependent ATPase activity [ISO]
- calcium-transporting ATPase activity [IDA, IMP, ISO, ISS, TAS]
- calmodulin binding [ISO, ISS]
- glutamate receptor binding [IPI]
- protein C-terminus binding [ISO, ISS]
- ATP binding [IDA, ISO, ISS]
- PDZ domain binding [IPI, ISO, ISS]
- acetylcholine receptor binding [IDA]
- calcium ion binding [ISO, ISS]
- calcium-dependent ATPase activity [ISO]
- calcium-transporting ATPase activity [IDA, IMP, ISO, ISS, TAS]
- calmodulin binding [ISO, ISS]
- glutamate receptor binding [IPI]
- protein C-terminus binding [ISO, ISS]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID