BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
RELN
Reelen, Rl, reeler
reelin
GO Process (66)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
- N-methyl-D-aspartate receptor clustering [ISO]
- associative learning [ISO]
- axon guidance [ISO, ISS]
- brain development [IMP, ISO, ISS]
- cell migration [ISO]
- cell morphogenesis involved in differentiation [ISO, ISS]
- cellular response to dexamethasone stimulus [IEP]
- central nervous system development [ISO, ISS]
- cerebral cortex development [IEP, ISO]
- cerebral cortex tangential migration [ISO, ISS]
- dendrite development [ISO]
- dentate gyrus development [IMP]
- forebrain development [ISO]
- glial cell differentiation [ISO, ISS]
- hippocampus development [ISO]
- hypothalamus development [IEP]
- lateral motor column neuron migration [ISO]
- layer formation in cerebral cortex [ISO]
- locomotory behavior [IMP, ISO]
- long-term memory [ISO]
- memory [IEP]
- midgut development [IEP]
- neuron migration [IMP, ISO, ISS]
- orbitofrontal cortex development [IEP]
- peptidyl-tyrosine phosphorylation [ISO, ISS]
- positive regulation of CREB transcription factor activity [ISO]
- positive regulation of TOR signaling [ISO]
- positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [ISO]
- positive regulation of dendritic spine morphogenesis [ISO]
- positive regulation of excitatory postsynaptic membrane potential [ISO]
- positive regulation of lateral motor column neuron migration [ISO]
- positive regulation of long-term synaptic potentiation [ISO]
- positive regulation of neuron projection development [ISO]
- positive regulation of peptidyl-tyrosine phosphorylation [ISO]
- positive regulation of phosphatidylinositol 3-kinase signaling [ISO]
- positive regulation of protein kinase activity [ISO, ISS]
- positive regulation of protein tyrosine kinase activity [ISO]
- positive regulation of small GTPase mediated signal transduction [ISO, ISS]
- positive regulation of synapse maturation [ISO]
- positive regulation of synaptic transmission, glutamatergic [ISO]
- postsynaptic density protein 95 clustering [ISO]
- protein localization to synapse [ISO]
- receptor localization to synapse [ISO]
- reelin-mediated signaling pathway [ISO]
- regulation of N-methyl-D-aspartate selective glutamate receptor activity [ISO]
- regulation of behavior [ISO]
- regulation of gene expression [ISO]
- regulation of synaptic transmission [ISO]
- response to amino acid [IEP]
- response to axon injury [IEP]
- response to corticosterone [IEP]
- response to drug [IEP]
- response to electrical stimulus [IEP]
- response to ethanol [IEP]
- response to fatty acid [IEP]
- response to hormone [IEP]
- response to insecticide [IEP]
- response to lithium ion [IEP]
- response to mechanical stimulus [IEP]
- response to organic cyclic compound [IEP]
- response to pain [ISO, ISS]
- response to progesterone [IEP]
- response to toxic substance [IEP]
- social behavior [IEP]
- spinal cord patterning [IEP, ISO, ISS]
- thyroid hormone metabolic process [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID