BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
SCN2B
SCNB2
sodium channel, voltage-gated, type II, beta subunit
GO Process (9)
GO Function (4)
GO Component (1)
Gene Ontology Biological Process
- cardiac muscle cell action potential involved in contraction [ISO]
- cardiac muscle contraction [ISO]
- membrane depolarization during cardiac muscle cell action potential [ISO]
- nervous system development [IEP]
- regulation of atrial cardiac muscle cell membrane depolarization [ISO]
- regulation of heart rate by cardiac conduction [ISO]
- regulation of sodium ion transmembrane transporter activity [ISO]
- response to pyrethroid [IDA]
- sodium ion transmembrane transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID