BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
SCN3B
Scnb3
sodium channel, voltage-gated, type III, beta subunit
GO Process (21)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- SA node cell to atrial cardiac muscle cell communication [ISO]
- atrial cardiac muscle cell action potential [ISO]
- cardiac conduction [ISO]
- cardiac muscle cell action potential involved in contraction [ISO]
- cardiac muscle contraction [ISO]
- membrane depolarization [ISO]
- membrane depolarization during action potential [ISO]
- membrane depolarization during cardiac muscle cell action potential [ISO]
- nervous system development [IEP]
- positive regulation of heart rate [ISO]
- positive regulation of sodium ion transport [ISO]
- protein localization to plasma membrane [ISO]
- regulation of atrial cardiac muscle cell membrane depolarization [ISO]
- regulation of heart rate by cardiac conduction [ISO]
- regulation of ion transmembrane transport [ISO]
- regulation of sodium ion transmembrane transporter activity [ISO]
- regulation of ventricular cardiac muscle cell membrane depolarization [ISO]
- sensory perception of pain [IEP]
- sodium ion transmembrane transport [ISO]
- sodium ion transport [IDA]
- ventricular cardiac muscle cell action potential [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID