BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
SNX3
sorting nexin 3
GO Process (17)
GO Function (6)
GO Component (12)
Gene Ontology Biological Process
- endocytosis [IBA]
- hemoglobin biosynthetic process [ISO]
- intralumenal vesicle formation [ISO]
- membrane invagination [ISO]
- negative regulation of early endosome to late endosome transport [ISO]
- negative regulation of phagocytosis [ISO, ISS]
- negative regulation of protein catabolic process [ISO]
- negative regulation of protein transport [ISO]
- negative regulation of viral entry into host cell [ISO]
- positive regulation of neuron projection development [ISS]
- protein to membrane docking [ISO, ISS]
- regulation of Wnt signaling pathway [ISO, ISS]
- regulation of cellular protein metabolic process [ISO]
- regulation of intracellular protein transport [ISO]
- response to bacterium [ISO]
- transferrin transport [ISO]
- vesicle organization [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- clathrin-coated vesicle [ISO, ISS]
- cytoplasm [ISO]
- cytosol [ISO]
- early endosome [ISO, ISS]
- early endosome membrane [ISO]
- early phagosome [ISO, ISS]
- endosome [IBA]
- endosome membrane [ISO, ISS]
- extracellular vesicular exosome [ISO]
- extrinsic component of membrane [IBA]
- intracellular membrane-bounded organelle [ISO]
- retromer complex [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID