BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
TXN1
Txn
thioredoxin 1
GO Process (19)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
- cell redox homeostasis [ISO]
- cellular response to antibiotic [IEP]
- cellular response to drug [IEP]
- cellular response to glucose stimulus [IEP]
- cellular response to hyperoxia [IEP]
- negative regulation of hydrogen peroxide-induced cell death [ISO]
- negative regulation of protein export from nucleus [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- oxidation-reduction process [ISO, ISS]
- positive regulation of DNA binding [ISO, ISS]
- positive regulation of peptidyl-serine phosphorylation [ISO]
- regulation of protein import into nucleus, translocation [ISO, ISS]
- response to activity [IEP]
- response to axon injury [IEP]
- response to dexamethasone [IEP]
- response to drug [IEP]
- response to radiation [ISO, ISS]
- response to selenium ion [IEP]
- response to thyroxine [IEP]
Gene Ontology Molecular Function
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID