BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
TXNIP
Vdup1
thioredoxin interacting protein
GO Process (17)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- cellular response to tumor cell [ISO, ISS]
- keratinocyte differentiation [ISO]
- negative regulation of catalytic activity [ISO]
- negative regulation of cell division [ISO, ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- platelet-derived growth factor receptor signaling pathway [ISO]
- positive regulation of apoptotic process [IMP]
- protein import into nucleus [ISO]
- regulation of cell proliferation [IDA]
- response to calcium ion [IEP]
- response to drug [IEP]
- response to estradiol [IEP]
- response to glucose [IEP]
- response to hydrogen peroxide [IEP]
- response to mechanical stimulus [IEP]
- response to oxidative stress [ISO]
- response to progesterone [IEP]
Gene Ontology Molecular Function
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID