BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
TRIM28
Kap1, Krip1, Tif1b
tripartite motif-containing 28
GO Process (21)
GO Function (12)
GO Component (6)
Gene Ontology Biological Process
- DNA methylation involved in embryo development [ISO]
- DNA repair [ISO]
- convergent extension involved in axis elongation [ISO]
- embryo implantation [ISO]
- embryonic placenta morphogenesis [ISO]
- epithelial to mesenchymal transition [ISO, ISS]
- in utero embryonic development [ISO]
- innate immune response [ISO]
- negative regulation of DNA demethylation [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- negative regulation of viral release from host cell [ISO]
- positive regulation of DNA repair [ISO]
- positive regulation of transcription factor import into nucleus [ISO, ISS]
- positive regulation of transcription, DNA-templated [ISO, ISS]
- protein autophosphorylation [ISO]
- protein oligomerization [ISO]
- protein phosphorylation [ISO]
- protein sumoylation [ISO]
- protein ubiquitination [ISO]
- regulation of genetic imprinting [ISO]
Gene Ontology Molecular Function- DNA binding [ISO]
- Krueppel-associated box domain binding [ISO, ISS]
- chromo shadow domain binding [ISO]
- poly(A) RNA binding [ISO]
- protein kinase activity [ISO]
- sequence-specific DNA binding [ISO, ISS]
- sequence-specific DNA binding transcription factor activity [ISO, ISS]
- transcription coactivator activity [ISO]
- transcription corepressor activity [ISO]
- ubiquitin protein ligase binding [ISO]
- ubiquitin-protein transferase activity [ISO]
- zinc ion binding [ISO]
- DNA binding [ISO]
- Krueppel-associated box domain binding [ISO, ISS]
- chromo shadow domain binding [ISO]
- poly(A) RNA binding [ISO]
- protein kinase activity [ISO]
- sequence-specific DNA binding [ISO, ISS]
- sequence-specific DNA binding transcription factor activity [ISO, ISS]
- transcription coactivator activity [ISO]
- transcription corepressor activity [ISO]
- ubiquitin protein ligase binding [ISO]
- ubiquitin-protein transferase activity [ISO]
- zinc ion binding [ISO]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID