BAIT
UBC
ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
FGR
p55-Fgr
FGR proto-oncogene, Src family tyrosine kinase
GO Process (20)
GO Function (8)
GO Component (7)
Gene Ontology Biological Process
- cell differentiation [IBA]
- cell migration [IBA]
- cellular response to peptide hormone stimulus [IBA]
- defense response to Gram-positive bacterium [ISO, ISS]
- innate immune response [IBA]
- integrin-mediated signaling pathway [IBA, ISO, ISS]
- peptidyl-tyrosine autophosphorylation [IBA]
- peptidyl-tyrosine phosphorylation [ISO, ISS]
- positive regulation of cell migration [ISO, ISS]
- positive regulation of cytokine secretion [ISO, ISS]
- positive regulation of mast cell degranulation [ISO, ISS]
- positive regulation of phosphatidylinositol 3-kinase activity [ISO]
- positive regulation of phosphatidylinositol 3-kinase signaling [ISO]
- protein autophosphorylation [ISO]
- regulation of cell proliferation [IBA]
- regulation of cell shape [ISO, ISS]
- regulation of innate immune response [ISO, ISS]
- regulation of phagocytosis [ISO, ISS]
- regulation of protein kinase activity [ISO, ISS]
- transmembrane receptor protein tyrosine kinase signaling pathway [IBA]
Gene Ontology Molecular Function- Fc-gamma receptor I complex binding [ISO]
- immunoglobulin receptor binding [ISO, ISS]
- non-membrane spanning protein tyrosine kinase activity [IBA, ISO]
- phosphotyrosine binding [ISO, ISS]
- protein binding [IPI]
- protein kinase binding [ISO, ISS]
- protein tyrosine kinase activity [IDA, ISO]
- receptor binding [IBA]
- Fc-gamma receptor I complex binding [ISO]
- immunoglobulin receptor binding [ISO, ISS]
- non-membrane spanning protein tyrosine kinase activity [IBA, ISO]
- phosphotyrosine binding [ISO, ISS]
- protein binding [IPI]
- protein kinase binding [ISO, ISS]
- protein tyrosine kinase activity [IDA, ISO]
- receptor binding [IBA]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Synaptic Protein Ubiquitination in Rat Brain Revealed by Antibody-based Ubiquitome Analysis.
Protein ubiquitination is an essential post-translational modification regulating neurodevelopment, synaptic plasticity, learning, and memory, and its dysregulation contributes to the pathogenesis of neurological diseases. Here we report a systematic analysis of ubiquitinated proteome (ubiquitome) in rat brain using a newly developed monoclonal antibody that recognizes the diglycine tag on lysine residues in trypsinized peptides (K-GG peptides). Initial antibody specificity analysis ... [more]
J. Proteome Res. Aug. 15, 2012; 0(0); [Pubmed: 22871113]
Throughput
- Low Throughput
Curated By
- BioGRID