STX3
Gene Ontology Biological Process
- exocytosis [IMP]
- intracellular protein transport [IBA]
- long-term synaptic potentiation [IMP]
- membrane fusion [ISO]
- neuron projection development [ISO]
- positive regulation of cell adhesion [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of chemotaxis [ISO]
- positive regulation of protein localization to cell surface [ISO]
- positive regulation of protein localization to plasma membrane [ISO]
- synaptic vesicle fusion to presynaptic membrane [IBA]
- vesicle docking [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- SNARE complex [IBA, ISO]
- apical plasma membrane [IDA, ISO]
- azurophil granule [ISO]
- cell [IMP]
- cell-cell junction [ISO]
- dendrite [IDA]
- extracellular vesicular exosome [ISO]
- growth cone [ISO]
- integral component of membrane [IBA]
- lamellipodium [ISO]
- membrane [IDA]
- neuron projection [ISO]
- plasma membrane [ISO]
- secretory granule [IDA]
- specific granule [ISO]
- synaptic vesicle [IBA]
STXBP2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- SNARE complex [ISO]
- apical plasma membrane [IDA, ISO]
- azurophil granule [ISO]
- cell [IMP]
- cytolytic granule [ISO]
- cytoplasm [ISO]
- cytosol [ISO]
- extracellular vesicular exosome [ISO]
- lamellipodium [ISO]
- plasma membrane [ISO]
- protein complex [ISO]
- secretory granule [ISO]
- specific granule [ISO]
- tertiary granule [ISO]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Syntaxin 3 and Munc-18-2 in epithelial cells during kidney development.
Differentiation of epithelial cells involves the assembly of polarized membrane transport machineries necessary for the generation and maintenance of the apical and basolateral membrane domains characteristic of this cell type. We have analyzed the expression patterns of vesicle-docking proteins of the syntaxin family in mouse kidney, focusing on syntaxin 3 and its interaction partner, the Sec1-related Munc-18-2.Expression patterns were studied ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| STX3 STXBP2 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID