SOX6
Gene Ontology Biological Process
- astrocyte differentiation [ISO]
- cardiac muscle cell differentiation [IDA]
- cartilage development [IGI]
- cell fate commitment [IGI]
- cell morphogenesis [IMP]
- cellular response to transforming growth factor beta stimulus [ISO]
- erythrocyte development [IMP]
- erythrocyte differentiation [IMP]
- gene silencing [IMP]
- hemopoiesis [IMP]
- in utero embryonic development [IMP]
- muscle cell differentiation [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- negative regulation of transcription, DNA-templated [IDA]
- oligodendrocyte cell fate specification [IMP]
- oligodendrocyte differentiation [IMP]
- positive regulation of cartilage development [ISO]
- positive regulation of chondrocyte differentiation [IDA, ISO]
- positive regulation of mesenchymal stem cell differentiation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IGI]
- positive regulation of transcription, DNA-templated [IDA]
- post-embryonic development [IMP]
- regulation of gene expression [IMP]
- regulation of transcription, DNA-templated [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
DAZAP2
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Sox6 regulation of cardiac myocyte development.
A mouse mutation (p100H/p100H) has been identified that is associated with cardioskeletal myopathy, heart block, delayed growth and early postnatal death. The gene that is disrupted in this mutation encodes the transcription factor Sox6. P19CL6 cells were used as an in vitro cardiomyocyte differentiation system and revealed that Sox6 is expressed exclusively when the cells are committed to differentiate to ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID