NMRK2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ITGB1
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IMP]
- axon extension [IGI, IMP]
- calcium-independent cell-matrix adhesion [ISO]
- cardiac muscle cell differentiation [IMP]
- cardiac muscle tissue development [IMP]
- cell adhesion [ISO]
- cell fate specification [IMP]
- cell migration [IMP]
- cell migration involved in sprouting angiogenesis [IMP]
- cell-matrix adhesion [IGI, IMP, ISO]
- cell-substrate adhesion [ISO]
- cellular calcium ion homeostasis [ISO]
- dendrite morphogenesis [IGI, IMP]
- formation of radial glial scaffolds [IMP]
- germ cell migration [IMP]
- heterotypic cell-cell adhesion [ISO]
- in utero embryonic development [IMP]
- integrin-mediated signaling pathway [ISO]
- leukocyte cell-cell adhesion [ISO]
- leukocyte tethering or rolling [ISO]
- negative regulation of Rho protein signal transduction [IGI]
- negative regulation of anoikis [ISO]
- negative regulation of cell differentiation [IMP]
- negative regulation of cell projection organization [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of neuron differentiation [ISO]
- neuron projection development [IMP]
- positive regulation of MAPK cascade [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of cell proliferation [IMP]
- positive regulation of cell-substrate adhesion [ISO]
- positive regulation of endocytosis [ISO]
- positive regulation of establishment of protein localization to plasma membrane [ISO]
- positive regulation of neuron differentiation [ISO]
- positive regulation of neuron projection development [ISO]
- positive regulation of peptidyl-tyrosine phosphorylation [ISO]
- protein transport within lipid bilayer [ISO]
- regulation of G-protein coupled receptor protein signaling pathway [ISO]
- regulation of cell cycle [IMP]
- regulation of collagen catabolic process [ISO]
- sarcomere organization [IMP]
- stress fiber assembly [IMP]
- tight junction assembly [ISO]
- tissue homeostasis [ISO]
- transforming growth factor beta receptor signaling pathway [IMP]
- visual learning [IGI, IMP]
Gene Ontology Molecular Function- actin binding [ISO]
- alpha-actinin binding [ISO]
- cell adhesion molecule binding [ISO]
- collagen binding [ISO]
- collagen binding involved in cell-matrix adhesion [ISO]
- fibronectin binding [ISO]
- glycoprotein binding [ISO]
- integrin binding [IPI, ISO]
- kinase binding [ISO]
- laminin binding [IDA, ISO]
- peptide binding [ISO]
- protease binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [ISO]
- protein heterodimerization activity [ISO]
- protein kinase binding [ISO]
- receptor binding [ISO]
- actin binding [ISO]
- alpha-actinin binding [ISO]
- cell adhesion molecule binding [ISO]
- collagen binding [ISO]
- collagen binding involved in cell-matrix adhesion [ISO]
- fibronectin binding [ISO]
- glycoprotein binding [ISO]
- integrin binding [IPI, ISO]
- kinase binding [ISO]
- laminin binding [IDA, ISO]
- peptide binding [ISO]
- protease binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [ISO]
- protein heterodimerization activity [ISO]
- protein kinase binding [ISO]
- receptor binding [ISO]
Gene Ontology Cellular Component
- acrosomal vesicle [ISO]
- adherens junction [ISO]
- basement membrane [ISO]
- cell surface [IDA, ISO]
- cell-cell junction [ISO]
- cytoplasm [ISO]
- cytoplasmic vesicle [IDA]
- dendritic spine [IDA]
- external side of plasma membrane [IDA]
- extracellular vesicular exosome [ISO]
- filopodium [ISO]
- focal adhesion [ISO]
- hemidesmosome [ISO]
- integrin alpha1-beta1 complex [ISO]
- integrin alpha10-beta1 complex [ISO]
- integrin alpha11-beta1 complex [ISO]
- integrin alpha2-beta1 complex [ISO]
- integrin alpha3-beta1 complex [ISO]
- integrin alpha7-beta1 complex [IDA, IPI]
- integrin alpha9-beta1 complex [ISO]
- integrin complex [ISO]
- intercalated disc [IDA]
- invadopodium membrane [ISO]
- membrane [ISO]
- membrane raft [ISO]
- myelin sheath abaxonal region [IDA]
- neuromuscular junction [IDA, ISO]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [IDA, ISO]
- receptor complex [ISO]
- ruffle membrane [ISO]
- sarcolemma [IDA, ISO]
- synapse [IDA]
- synaptic membrane [IDA]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
A novel muscle-specific beta 1 integrin binding protein (MIBP) that modulates myogenic differentiation.
Myogenesis is regulated by cell adhesion receptors, including integrins of the beta1 family. We report the identification of a novel muscle-specific beta1 integrin binding protein (MIBP). MIBP binds to the membrane-proximal cytoplasmic region shared by beta1A and beta1D integrins, and the binding occurs in vivo as well as in vitro. Furthermore, we show that MIBP is abundantly expressed by C2C12 ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ITGB1 NMRK2 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID