BAIT

MARCH2

MARCH-II, RGD1306395
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
GO Process (1)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Rattus norvegicus
PREY

UBC

ubiquitin C
GO Process (2)
GO Function (2)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Rattus norvegicus

Biochemical Activity (Ubiquitination)

An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.

Publication

MARCH-III Is a novel component of endosomes with properties similar to those of MARCH-II.

Fukuda H, Nakamura N, Hirose S

MARCH comprises a recently identified family of transmembrane RING-finger proteins which is implicated in diverse biological functions, such as immune regulation, protein quality control, and membrane trafficking. We previously identified MARCH-II, as a binding partner of syntaxin 6, which plays a role in endosomal protein transport. In this paper, we describe the cloning and characterization of MARCH-III which is the ... [more]

J. Biochem. Jan. 01, 2006; 139(1);137-45 [Pubmed: 16428329]

Throughput

  • Low Throughput

Additional Notes

  • E2 - ubcH5C, ubcH6, and ubcH9
  • rabbit E1

Curated By

  • BioGRID