SMYD1
Gene Ontology Biological Process
Gene Ontology Molecular Function
NACA
Gene Ontology Biological Process
- cardiac ventricle development [IMP]
- heart trabecula morphogenesis [IMP]
- myoblast migration [IMP]
- negative regulation of striated muscle cell apoptotic process [IMP]
- negative regulation of transcription from RNA polymerase II promoter involved in heart development [IMP]
- positive regulation of cell proliferation involved in heart morphogenesis [IMP]
- positive regulation of skeletal muscle tissue growth [IMP]
- positive regulation of transcription from RNA polymerase II promoter involved in heart development [IMP]
- regulation of nucleic acid-templated transcription [IDA]
- regulation of skeletal muscle fiber development [IMP]
- skeletal muscle tissue regeneration [IMP]
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
m-Bop, a repressor protein essential for cardiogenesis, interacts with skNAC, a heart- and muscle-specific transcription factor.
The m-Bop protein encoded by the mouse Bop gene is strongly expressed in heart and skeletal muscle, and recent studies with Bop knockout mice have demonstrated that m-Bop is essential for cardiogenesis in vivo and can act as a HDAC-dependent repressor in vitro. In the present studies, m-Bop was observed to interact with skNAC, a reported transcriptional activator specific to ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID