BAIT
AQP2
AQP-CD, WCH-CD, cph, jpk
aquaporin 2
GO Process (14)
GO Function (6)
GO Component (20)
Gene Ontology Biological Process
- actin filament depolymerization [ISO]
- apoptotic process [ISO]
- carbohydrate transmembrane transport [IBA]
- cell volume homeostasis [ISO]
- cellular response to copper ion [ISO]
- cellular response to mercury ion [ISO]
- cellular response to water deprivation [IDA, ISO]
- cellular water homeostasis [IBA]
- glycerol transport [IBA, ISO]
- ion transmembrane transport [IBA]
- positive regulation of calcium ion transport [ISO]
- renal water transport [IMP]
- transmembrane transport [IDA]
- water transport [IDA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apical plasma membrane [IDA, ISO]
- basolateral plasma membrane [ISO]
- clathrin-coated vesicle [ISO]
- cytoplasm [ISO]
- cytoplasmic vesicle [IDA]
- early endosome [ISO]
- exocytic vesicle [ISO]
- extracellular vesicular exosome [ISO]
- integral component of endosome membrane [IC]
- integral component of membrane [ISM]
- integral component of plasma membrane [IBA, IC]
- lysosome [ISO]
- membrane [IDA, ISO]
- plasma membrane [IDA, ISO]
- protein complex [ISO]
- recycling endosome [IDA]
- recycling endosome membrane [IC]
- rough endoplasmic reticulum [ISO]
- trans-Golgi network [ISO]
- transport vesicle [ISO]
Mus musculus
PREY
VAMP2
Syb-2, Syb2, sybII, RP23-26L6.8
vesicle-associated membrane protein 2
GO Process (15)
GO Function (12)
GO Component (23)
Gene Ontology Biological Process
- Golgi to plasma membrane protein transport [IMP]
- calcium ion-dependent exocytosis [IDA, IMP]
- cellular response to insulin stimulus [IDA]
- eosinophil degranulation [ISO]
- long-term synaptic potentiation [IMP]
- membrane fusion [IMP]
- positive regulation of intracellular protein transport [IMP]
- protein complex assembly [ISO]
- protein transport [ISO]
- regulation of exocytosis [IDA, ISO]
- regulation of vesicle-mediated transport [IMP]
- response to glucose [ISO]
- synaptic vesicle exocytosis [IMP]
- vesicle fusion [IBA]
- vesicle-mediated transport [ISO]
Gene Ontology Molecular Function- SNAP receptor activity [IBA]
- SNARE binding [IDA, ISO]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- identical protein binding [ISO]
- myosin binding [ISO]
- phospholipid binding [IDA]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- syntaxin binding [IPI, ISO]
- syntaxin-1 binding [ISO]
- SNAP receptor activity [IBA]
- SNARE binding [IDA, ISO]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- identical protein binding [ISO]
- myosin binding [ISO]
- phospholipid binding [IDA]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- syntaxin binding [IPI, ISO]
- syntaxin-1 binding [ISO]
Gene Ontology Cellular Component
- SNARE complex [ISO]
- cell [IMP]
- clathrin-coated vesicle [ISO]
- cytoplasmic vesicle [IDA]
- extracellular vesicular exosome [ISO]
- intracellular [IMP]
- intracellular membrane-bounded organelle [ISO]
- intracellular organelle [ISO]
- membrane [ISO]
- neuron projection [ISO]
- neuron projection terminus [ISO]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [IDA, ISO]
- secretory granule [IDA, ISO]
- synapse [IDA]
- synaptic vesicle [IDA, ISO]
- synaptic vesicle membrane [IDA]
- synaptobrevin 2-SNAP-25-syntaxin-1a complex [IDA, ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex [ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex [ISO]
- terminal bouton [ISO]
- trans-Golgi network [IDA]
- zymogen granule membrane [IDA]
Mus musculus
Co-purification
An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps.
Publication
AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b.
Vasopressin regulates the fusion of the water channel aquaporin 2 (AQP2) to the apical membrane of the renal collecting-duct principal cells and several lines of evidence indicate that SNARE proteins mediate this process. In this work MCD4 renal cells were used to investigate the functional role of a set of Q- and R-SNAREs, together with that of Munc18b as a ... [more]
J. Cell. Sci. Jun. 15, 2008; 121(0);2097-106 [Pubmed: 18505797]
Throughput
- Low Throughput
Curated By
- BioGRID