BAIT
AQP2
AQP-CD, WCH-CD, cph, jpk
aquaporin 2
GO Process (14)
GO Function (6)
GO Component (20)
Gene Ontology Biological Process
- actin filament depolymerization [ISO]
- apoptotic process [ISO]
- carbohydrate transmembrane transport [IBA]
- cell volume homeostasis [ISO]
- cellular response to copper ion [ISO]
- cellular response to mercury ion [ISO]
- cellular response to water deprivation [IDA, ISO]
- cellular water homeostasis [IBA]
- glycerol transport [IBA, ISO]
- ion transmembrane transport [IBA]
- positive regulation of calcium ion transport [ISO]
- renal water transport [IMP]
- transmembrane transport [IDA]
- water transport [IDA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apical plasma membrane [IDA, ISO]
- basolateral plasma membrane [ISO]
- clathrin-coated vesicle [ISO]
- cytoplasm [ISO]
- cytoplasmic vesicle [IDA]
- early endosome [ISO]
- exocytic vesicle [ISO]
- extracellular vesicular exosome [ISO]
- integral component of endosome membrane [IC]
- integral component of membrane [ISM]
- integral component of plasma membrane [IBA, IC]
- lysosome [ISO]
- membrane [IDA, ISO]
- plasma membrane [IDA, ISO]
- protein complex [ISO]
- recycling endosome [IDA]
- recycling endosome membrane [IC]
- rough endoplasmic reticulum [ISO]
- trans-Golgi network [ISO]
- transport vesicle [ISO]
Mus musculus
PREY
VAMP3
D130027G05Rik, VAMP-3, ceb, RP23-455G15.3
vesicle-associated membrane protein 3
GO Process (11)
GO Function (4)
GO Component (15)
Gene Ontology Biological Process
- Golgi to plasma membrane protein transport [IMP]
- SNARE complex assembly [IDA]
- calcium ion-dependent exocytosis [IMP]
- negative regulation of secretion by cell [ISO]
- neurotransmitter secretion [IBA]
- positive regulation of receptor recycling [IDA]
- protein complex assembly [ISO]
- retrograde transport, endosome to Golgi [ISO]
- substrate adhesion-dependent cell spreading [IDA]
- vesicle fusion [IBA]
- vesicle-mediated transport [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- SNARE complex [IBA, ISO]
- apical plasma membrane [ISO]
- cell [IMP]
- cell surface [IDA]
- clathrin-coated vesicle [ISO]
- clathrin-coated vesicle membrane [ISO]
- cytoplasmic vesicle [IDA]
- cytosol [IDA, ISO]
- intracellular [IMP, ISO]
- intracellular membrane-bounded organelle [ISO]
- intracellular organelle [ISO]
- plasma membrane [IDA, ISO]
- recycling endosome [ISO]
- secretory granule [IDA]
- synaptic vesicle [IBA]
Mus musculus
Co-purification
An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps.
Publication
AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b.
Vasopressin regulates the fusion of the water channel aquaporin 2 (AQP2) to the apical membrane of the renal collecting-duct principal cells and several lines of evidence indicate that SNARE proteins mediate this process. In this work MCD4 renal cells were used to investigate the functional role of a set of Q- and R-SNAREs, together with that of Munc18b as a ... [more]
J. Cell. Sci. Jun. 15, 2008; 121(0);2097-106 [Pubmed: 18505797]
Throughput
- Low Throughput
Curated By
- BioGRID