NRIP2
Gene Ontology Biological Process
Gene Ontology Molecular Function
RORB
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [ISO]
- amacrine cell differentiation [IMP]
- cellular response to retinoic acid [ISO]
- eye photoreceptor cell development [IMP]
- negative regulation of osteoblast differentiation [IDA]
- negative regulation of transcription, DNA-templated [ISO]
- positive regulation of transcription, DNA-templated [IDA, ISO]
- regulation of circadian rhythm [IMP]
- retina development in camera-type eye [IMP]
- retinal cone cell development [IDA]
- retinal rod cell development [IMP]
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Differential ligand-dependent protein-protein interactions between nuclear receptors and a neuronal-specific cofactor.
Nuclear receptors are transcription factors that require multiple protein-protein interactions to regulate target gene expression. We have cloned a 27-kDa protein, termed NIX1 (neuronal interacting factor X 1), that directly binds nuclear receptors in vitro and in vivo. Protein-protein interaction between NIX1 and ligand-activated or constitutive active nuclear receptors, including retinoid-related orphan receptor beta (RORbeta) (NR1F2), strictly depends on the ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID