BAIT
RFPL4
D7Ertd486e, Rfpl4a
ret finger protein-like 4
GO Process (0)
GO Function (1)
GO Component (3)
Mus musculus
PREY
UBE2A
HHR6A, HR6A, Mhr6a, RP23-286I5.4
ubiquitin-conjugating enzyme E2A
GO Process (13)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- DNA repair [IBA, ISO]
- histone H2A ubiquitination [ISO]
- histone ubiquitination [IBA]
- in utero embryonic development [IGI, IMP]
- maternal process involved in female pregnancy [IMP]
- positive regulation of cell proliferation [ISO]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IBA]
- protein K11-linked ubiquitination [ISO]
- protein K48-linked ubiquitination [ISO]
- protein autoubiquitination [ISO]
- protein polyubiquitination [IBA]
- protein ubiquitination [IGI]
- response to UV [ISO]
Gene Ontology Molecular Function
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
RFPL4 interacts with oocyte proteins of the ubiquitin-proteasome degradation pathway.
Oocyte meiosis and early mitotic divisions in developing embryos rely on the timely production of cell cycle regulators and their clearance via proteasomal degradation. Ret Finger Protein-Like 4 (Rfpl4), encoding a RING finger-like protein with a B30.2 domain, was discovered during an in silico search for germ cell-specific genes. To study the expression and functions of RFPL4 protein, we performed ... [more]
Proc. Natl. Acad. Sci. U.S.A. Jan. 21, 2003; 100(2);550-5 [Pubmed: 12525704]
Throughput
- Low Throughput
Curated By
- BioGRID