BAIT
CABYR
1700016C01Rik, 4933421A18Rik, CBP86, FSP-2
calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
GO Process (3)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
MAPK8IP3
BB120594, D17Wsu15e, JIP-3, JSAP1, JSAP1a, JSAP1b, JSAP1c, JSAP1d, Jip3, Syd2, mKIAA1066
mitogen-activated protein kinase 8 interacting protein 3
GO Process (16)
GO Function (7)
GO Component (7)
Gene Ontology Biological Process
- JNK cascade [IDA]
- activation of JUN kinase activity [IDA]
- axon guidance [IMP]
- forebrain development [IMP]
- in utero embryonic development [IMP]
- lung alveolus development [IMP]
- lung morphogenesis [IMP]
- positive regulation of JUN kinase activity [IDA]
- positive regulation of neuron differentiation [ISO]
- positive regulation of signal transduction [IPI]
- post-embryonic development [IMP]
- protein localization [IMP]
- regulation of JNK cascade [IDA]
- regulation of gene expression [IDA]
- respiratory gaseous exchange [IMP]
- vesicle-mediated transport [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
FSCB, a novel protein kinase A-phosphorylated calcium-binding protein, is a CABYR-binding partner involved in late steps of fibrous sheath biogenesis.
We report characterization of a novel testis- and sperm-specific protein, FSCB (fibrous sheath CABYR binding), that is expressed post-meiotically and localized in mouse sperm flagella. FSCB was identified as a binding partner of CABYR, a calcium-binding protein that is tyrosine-phosphorylated during capacitation. Orthologous genes of FSCB are present in other mammals, including rat and human, and conserved motifs in FSCB ... [more]
J. Biol. Chem. Nov. 23, 2007; 282(47);34104-19 [Pubmed: 17855365]
Throughput
- Low Throughput
Curated By
- BioGRID