BAIT

CABYR

1700016C01Rik, 4933421A18Rik, CBP86, FSP-2
calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
Mus musculus
PREY

FSCB

EG623046
fibrous sheath CABYR binding protein
GO Process (0)
GO Function (2)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

FSCB, a novel protein kinase A-phosphorylated calcium-binding protein, is a CABYR-binding partner involved in late steps of fibrous sheath biogenesis.

Li YF, He W, Jha KN, Klotz K, Kim YH, Mandal A, Pulido S, Digilio L, Flickinger CJ, Herr JC

We report characterization of a novel testis- and sperm-specific protein, FSCB (fibrous sheath CABYR binding), that is expressed post-meiotically and localized in mouse sperm flagella. FSCB was identified as a binding partner of CABYR, a calcium-binding protein that is tyrosine-phosphorylated during capacitation. Orthologous genes of FSCB are present in other mammals, including rat and human, and conserved motifs in FSCB ... [more]

J. Biol. Chem. Nov. 23, 2007; 282(47);34104-19 [Pubmed: 17855365]

Throughput

  • Low Throughput

Curated By

  • BioGRID