BAIT
FBXO32
4833442G10Rik, AI430017, ATROGIN1, Gm20361, MAFbx
F-box protein 32
GO Process (4)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
ENO1
0610008I15, AL022784, Eno-1, MBP-1
enolase 1, alpha non-neuron
GO Process (3)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification of Atrogin-1 targeted proteins during the Myostatin-induced skeletal muscle wasting.
Atrogin-1, a muscle-specific E3 ligase, targets MyoD for degradation through the ubiquitin-proteasome mediated system. Myostatin, a member of the TGF-β superfamily, potently inhibits myogenesis by lowering MyoD levels. While Atrogin-1 is up-regulated by Myostatin, it is currently unknown whether Atrogin-1 plays a role in mediating Myostatin signaling to regulate myogenesis. In this report, we have confirmed that Atrogin-1 increasingly interacts ... [more]
Unknown Jun. 06, 2012; 0(0); [Pubmed: 22673621]
Throughput
- Low Throughput
Curated By
- BioGRID