BAIT
SYP
A230093K24Rik, AI848995, Syn, p38, RP23-54C14.4
synaptophysin
GO Process (6)
GO Function (7)
GO Component (13)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- excitatory synapse [IDA, ISO]
- integral component of synaptic vesicle membrane [IBA, TAS]
- intracellular organelle [ISO]
- membrane [IDA]
- neuron projection [ISO]
- neuron projection terminus [IDA, ISO]
- presynaptic active zone [IDA, ISO]
- presynaptic membrane [IDA]
- protein complex [ISO]
- synapse [IDA]
- synaptic vesicle [IDA, ISO]
- synaptic vesicle membrane [IDA]
- terminal bouton [ISO]
Mus musculus
PREY
SCAMP1
4930505M11Rik, AI415563, AW122395
secretory carrier membrane protein 1
GO Process (3)
GO Function (2)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
FRET
An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.
Publication
Interaction assays in yeast and cultured cells confirm known and identify novel partners of the synaptic vesicle protein synaptophysin.
Synaptophysin (SYP) is a major protein of neurotransmitter-containing vesicles spanning the membrane four times and contributing to various aspects of the synaptic vesicle cycle. The split-ubiquitin yeast two-hybrid system was used to characterize molecular interactions of membrane-bound, full-length murine SYP. In this way, the known homophilic SYP-SYP association could be confirmed and heterophilic binding of SYP to other tetraspan vesicle ... [more]
Neuroscience Oct. 02, 2008; 156(2);344-52 [Pubmed: 18706977]
Throughput
- Low Throughput
Curated By
- BioGRID