BAIT

JAKMIP1

5830437M04Rik, C330021K24Rik, Gababrbp, Marlin-1
janus kinase and microtubule interacting protein 1
GO Process (0)
GO Function (3)
GO Component (3)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus
PREY

KIF1B

A530096N05Rik, AI448212, AI506502, D4Mil1e, KIF1Bp130, KIF1Bp204, RP23-249G3.1
kinesin family member 1B
Mus musculus

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport.

Vidal RL, Ramirez OA, Sandoval L, Koenig-Robert R, Haertel S, Couve A

The cytoskeleton and cytoskeletal motors play a fundamental role in neurotransmitter receptor trafficking, but proteins that link GABA(B) receptors (GABA(B)Rs) to the cytoskeleton have not been described. We recently identified Marlin-1, a protein that interacts with GABA(B)R1. Here, we explore the association of GABA(B)Rs and Marlin-1 to the cytoskeleton using a combination of biochemistry, microscopy and live cell imaging. Our ... [more]

Mol. Cell. Neurosci. Jul. 01, 2007; 35(3);501-12 [Pubmed: 17532644]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
JAKMIP1 KIF1B
Co-fractionation
Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

Low-BioGRID
-

Curated By

  • BioGRID