BAIT
JAKMIP1
5830437M04Rik, C330021K24Rik, Gababrbp, Marlin-1
janus kinase and microtubule interacting protein 1
GO Process (0)
GO Function (3)
GO Component (3)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
GABBR1
GABAB1, GABAbR1, bM573K1.1
gamma-aminobutyric acid (GABA) B receptor, 1
GO Process (13)
GO Function (3)
GO Component (18)
Gene Ontology Biological Process
- adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway [ISO]
- gamma-aminobutyric acid signaling pathway [IDA, ISO]
- negative regulation of adenylate cyclase activity [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of dopamine secretion [ISO]
- negative regulation of epinephrine secretion [ISO]
- negative regulation of gamma-aminobutyric acid secretion [ISO]
- negative regulation of synaptic transmission [ISO]
- osteoblast differentiation [ISO]
- positive regulation of glutamate secretion [ISO]
- positive regulation of growth hormone secretion [ISO]
- regulation of cAMP biosynthetic process [ISO]
- regulation of glutamate secretion [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- G-protein coupled receptor dimeric complex [IDA]
- G-protein coupled receptor heterodimeric complex [ISO]
- axolemma [ISO]
- cytoplasm [IDA]
- dendritic shaft [ISO]
- dendritic spine [ISO]
- endoplasmic reticulum membrane [ISO]
- extracellular space [ISO]
- integral component of plasma membrane [ISO]
- intracellular membrane-bounded organelle [ISO]
- membrane [IDA]
- membrane raft [ISO]
- mitochondrial membrane [ISO]
- neuron projection [ISO]
- neuronal cell body [ISO]
- postsynaptic membrane [IDA]
- presynaptic membrane [IDA]
- synaptic vesicle [ISO]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport.
The cytoskeleton and cytoskeletal motors play a fundamental role in neurotransmitter receptor trafficking, but proteins that link GABA(B) receptors (GABA(B)Rs) to the cytoskeleton have not been described. We recently identified Marlin-1, a protein that interacts with GABA(B)R1. Here, we explore the association of GABA(B)Rs and Marlin-1 to the cytoskeleton using a combination of biochemistry, microscopy and live cell imaging. Our ... [more]
Mol. Cell. Neurosci. Jul. 01, 2007; 35(3);501-12 [Pubmed: 17532644]
Throughput
- Low Throughput
Curated By
- BioGRID