BAIT
ELAVL1
ELAV1, HUR, Hua, MelG
ELAV like RNA binding protein 1
GO Process (8)
GO Function (9)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
PLAUR
CD87, U-PAR, UPAR, URKR
plasminogen activator, urokinase receptor
GO Process (11)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
- C-terminal protein lipidation [TAS]
- attachment of GPI anchor to protein [TAS]
- blood coagulation [NAS, TAS]
- cellular component movement [NAS]
- cellular protein metabolic process [TAS]
- chemotaxis [TAS]
- fibrinolysis [TAS]
- post-translational protein modification [TAS]
- regulation of proteolysis [NAS]
- signal transduction [TAS]
- urokinase plasminogen activator signaling pathway [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2.
The mRNAs of urokinase plasminogen activator (uPA) and its receptor, uPAR, contain instability-determining AU-rich elements (AREs) in their 3' untranslated regions. The cellular proteins binding to these RNA sequences (ARE(uPA/uPAR)) are not known. We show here that the mRNA-stabilizing factor HuR functionally interacts with these sequences. HuR stabilized an ARE(uPA)-containing RNA substrate in vitro and stabilized in HeLa Tet-off cells ... [more]
Mol. Cell. Biol. Oct. 01, 2003; 23(20);7177-88 [Pubmed: 14517288]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| PLAUR ELAVL1 | Protein-RNA Protein-RNA An interaction is detected between and protein and an RNA in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID