FGFBP1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
FGF2
Gene Ontology Biological Process
- activation of MAPKK activity [IDA]
- angiogenesis [IDA, IGI]
- angiogenesis involved in coronary vascular morphogenesis [ISO]
- branching involved in ureteric bud morphogenesis [ISO]
- cardiac muscle cell proliferation [TAS]
- cell migration involved in sprouting angiogenesis [ISO]
- chondroblast differentiation [ISO]
- corticotropin hormone secreting cell differentiation [IDA]
- embryo development ending in birth or egg hatching [ISO]
- fibroblast growth factor receptor signaling pathway [IGI, ISO]
- glial cell differentiation [IMP]
- hyaluronan catabolic process [ISO]
- inositol phosphate biosynthetic process [ISO]
- lung development [IDA, IGI]
- mammary gland epithelial cell differentiation [IDA]
- negative regulation of blood vessel endothelial cell migration [ISO]
- negative regulation of cell death [ISO]
- negative regulation of cell proliferation [IGI]
- negative regulation of fibroblast migration [ISO]
- negative regulation of wound healing [ISO]
- organ induction [IDA]
- phosphatidylinositol biosynthetic process [ISO]
- positive chemotaxis [ISO]
- positive regulation of ERK1 and ERK2 cascade [IDA, ISO]
- positive regulation of angiogenesis [IDA, IGI, ISO]
- positive regulation of blood vessel endothelial cell migration [ISO]
- positive regulation of canonical Wnt signaling pathway [IDA]
- positive regulation of cardiac muscle cell proliferation [ISO]
- positive regulation of cell differentiation [IDA]
- positive regulation of cell fate specification [ISO]
- positive regulation of cell proliferation [IDA, IGI, ISO]
- positive regulation of cerebellar granule cell precursor proliferation [IDA]
- positive regulation of endothelial cell migration [IDA]
- positive regulation of endothelial cell proliferation [IDA, ISO]
- positive regulation of epithelial cell proliferation [IDA]
- positive regulation of gene expression [IDA]
- positive regulation of osteoblast differentiation [IGI]
- positive regulation of phosphatidylinositol 3-kinase activity [ISO]
- positive regulation of phospholipase C activity [ISO]
- positive regulation of protein kinase B signaling [IDA]
- positive regulation of protein phosphorylation [IDA]
- positive regulation of smooth muscle cell proliferation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, ISO]
- positive regulation of transcription, DNA-templated [ISO, TAS]
- regulation of cell cycle [IDA]
- regulation of retinal cell programmed cell death [IDA]
- release of sequestered calcium ion into cytosol [ISO]
- response to axon injury [IMP]
- stem cell development [IMP]
- substantia nigra development [IMP]
- thyroid-stimulating hormone-secreting cell differentiation [IDA]
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair.
The fibroblast growth factor-binding protein (FGF-BP) binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. In this study, we identified novel binding partners of FGF-BP, and we provide evidence for a role of this protein in epithelial repair processes. We show that expression of FGF-BP increases after injury to murine and human skin, in particular in keratinocytes. This ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID