FGFBP1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
FGF7
Gene Ontology Biological Process
- actin cytoskeleton reorganization [ISO]
- branching involved in salivary gland morphogenesis [IDA]
- fibroblast growth factor receptor signaling pathway [ISO]
- hair follicle morphogenesis [IMP]
- lung development [ISO]
- mesenchymal cell proliferation [ISO]
- ovarian follicle development [ISO]
- phosphatidylcholine biosynthetic process [ISO]
- phospholipid biosynthetic process [ISO]
- positive chemotaxis [ISO]
- positive regulation of cell proliferation [IDA, IGI, ISO]
- positive regulation of epithelial cell proliferation [IDA, ISO]
- positive regulation of epithelial cell proliferation involved in lung morphogenesis [ISO]
- positive regulation of keratinocyte migration [ISO]
- positive regulation of keratinocyte proliferation [ISO]
- positive regulation of peptidyl-tyrosine phosphorylation [ISO]
- protein localization to cell surface [ISO]
- regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [IDA]
- secretion by lung epithelial cell involved in lung growth [ISO]
- surfactant homeostasis [ISO]
- wound healing [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair.
The fibroblast growth factor-binding protein (FGF-BP) binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. In this study, we identified novel binding partners of FGF-BP, and we provide evidence for a role of this protein in epithelial repair processes. We show that expression of FGF-BP increases after injury to murine and human skin, in particular in keratinocytes. This ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID