NDE1
Gene Ontology Biological Process
- centrosome duplication [IMP]
- centrosome localization [IBA]
- cerebral cortex development [IGI, ISO]
- chromosome segregation [IBA]
- establishment of chromosome localization [IBA, ISO]
- establishment of mitotic spindle orientation [IBA, ISO]
- forebrain development [IMP]
- microtubule nucleation [IDA]
- microtubule organizing center organization [IMP]
- mitotic centrosome separation [IBA]
- neuroblast proliferation [IMP]
- neuron migration [IMP]
- vesicle transport along microtubule [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
DYNLL1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Mutually exclusive cytoplasmic dynein regulation by NudE-Lis1 and dynactin.
Cytoplasmic dynein is responsible for a wide range of cellular roles. How this single motor protein performs so many functions has remained a major outstanding question for many years. Part of the answer is thought to lie in the diversity of dynein regulators, but how the effects of these factors are coordinated in vivo remains unexplored. We previously found NudE ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID