BAIT
LMNB1
ADLD, LMN, LMN2, LMNB
lamin B1
GO Process (2)
GO Function (0)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
URB2
KIAA0133, NET10, NPA2, RP11-108F13.1
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
GO Process (0)
GO Function (0)
GO Component (3)
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Lco1 is a novel widely expressed lamin-binding protein in the nuclear interior.
A-type lamins are localized at the nuclear envelope and in the nucleoplasm, and are implicated in human diseases called laminopathies. In a yeast two-hybrid screen with lamin C, we identified a novel widely expressed 171-kDa protein that we named Lamin companion 1 (Lco1). Three independent biochemical assays showed direct binding of Lco1 to the C-terminal tail of A-type lamins with ... [more]
Exp. Cell Res. Aug. 15, 2004; 298(2);499-511 [Pubmed: 15265697]
Throughput
- Low Throughput
Curated By
- BioGRID