BAIT

ZSWIM7

SWS1
zinc finger, SWIM-type containing 7
GO Process (2)
GO Function (1)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

HSPA9

CRP40, CSA, GRP-75, GRP75, HEL-S-124m, HSPA9B, MOT, MOT2, MTHSP75, PBP74
heat shock 70kDa protein 9 (mortalin)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

hSWS1·SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair.

Liu T, Wan L, Wu Y, Chen J, Huang J

The Shu complex in yeast plays an important role in the homologous recombination pathway, which is critical for the maintenance of genomic integrity. The identification of human SWS1 (hSWS1) as the homolog of budding yeast Shu2 implicated that the Shu complex is evolutionarily conserved. However, the human counterparts of other components in this complex have not yet been identified and ... [more]

J. Biol. Chem. Dec. 02, 2011; 286(48);41758-66 [Pubmed: 21965664]

Throughput

  • Low Throughput

Curated By

  • BioGRID