ATP1A2
Gene Ontology Biological Process
- ATP hydrolysis coupled proton transport [IMP]
- adult locomotory behavior [ISO]
- cardiac muscle contraction [IC]
- cellular potassium ion homeostasis [ISO]
- cellular response to mechanical stimulus [IDA, IEP]
- cellular response to steroid hormone stimulus [IMP, ISO]
- cellular sodium ion homeostasis [ISO]
- energy coupled proton transmembrane transport, against electrochemical gradient [TAS]
- locomotion [ISO]
- negative regulation of calcium ion transmembrane transport [IMP]
- negative regulation of calcium:sodium antiporter activity [IMP]
- negative regulation of cytosolic calcium ion concentration [ISO]
- negative regulation of heart contraction [ISO]
- negative regulation of striated muscle contraction [ISO]
- neurotransmitter uptake [ISO]
- potassium ion import [ISO]
- potassium ion transport [IDA]
- regulation of blood pressure [ISO]
- regulation of cardiac muscle cell contraction [IMP]
- regulation of cardiac muscle contraction by calcium ion signaling [IC]
- regulation of muscle contraction [ISO]
- regulation of respiratory gaseous exchange by neurological system process [ISO]
- regulation of smooth muscle contraction [ISO]
- regulation of striated muscle contraction [ISO]
- regulation of the force of heart contraction [ISO]
- regulation of vasoconstriction [ISO]
- relaxation of cardiac muscle [IC]
- response to glycoside [IMP, ISO]
- response to nicotine [IDA]
- sodium ion export from cell [ISO]
- sodium ion transmembrane transport [IDA]
- sodium ion transport [IDA]
- visual learning [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ATP2B1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apical part of cell [IDA]
- apical plasma membrane [IDA]
- basolateral plasma membrane [IDA]
- cytoplasmic side of plasma membrane [IDA]
- dendrite membrane [IDA]
- dendritic spine membrane [IDA]
- extracellular vesicular exosome [ISO]
- membrane [ISO]
- membrane raft [IDA]
- neuronal cell body membrane [IDA]
- nucleus [ISO]
- plasma membrane [ISO]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Plasma membrane-cytoskeleton-endoplasmic reticulum complexes in neurons and astrocytes.
The possibility that certain integral plasma membrane (PM) proteins involved in Ca(2+) homeostasis form junctional units with adjacent endoplasmic reticulum (ER) in neurons and glia was explored using immunoprecipitation and immunocytochemistry. Rat brain membranes were solubilized with the mild, non-ionic detergent, IGEPAL CA-630. Na(+)/Ca(2+) exchanger type 1 (NCX1), a key PM Ca(2+) transporter, was immunoprecipitated from the detergent-soluble fraction. Several ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID