ATP1A3
Gene Ontology Biological Process
- ATP hydrolysis coupled proton transport [TAS]
- adult locomotory behavior [ISO]
- cellular potassium ion homeostasis [ISO]
- cellular sodium ion homeostasis [ISO]
- ionotropic glutamate receptor signaling pathway [ISO]
- memory [ISO]
- potassium ion import [ISO]
- potassium ion transport [IDA]
- response to drug [ISO]
- sodium ion export from cell [ISO]
- sodium ion transmembrane transport [ISS]
- sodium ion transport [IDA]
- visual learning [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ANK2
Gene Ontology Biological Process
- SA node cell action potential [ISO]
- SA node cell to atrial cardiac muscle cell communication [ISO]
- T-tubule organization [ISO]
- atrial cardiac muscle cell action potential [ISO]
- atrial cardiac muscle cell to AV node cell communication [ISO]
- atrial septum development [ISO]
- cardiac muscle contraction [ISO]
- cellular calcium ion homeostasis [ISO]
- cellular protein localization [ISO]
- nervous system development [IEP]
- paranodal junction assembly [IEP]
- positive regulation of calcium ion transmembrane transporter activity [ISO]
- positive regulation of calcium ion transport [ISO]
- positive regulation of cation channel activity [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of potassium ion transmembrane transporter activity [ISO]
- positive regulation of potassium ion transport [ISO]
- protein localization [ISO]
- protein localization to M-band [ISO]
- protein localization to T-tubule [ISO]
- protein localization to cell surface [ISO]
- protein localization to endoplasmic reticulum [ISO]
- protein localization to organelle [ISO]
- protein localization to plasma membrane [ISO]
- protein stabilization [ISO]
- protein targeting to plasma membrane [ISO]
- regulation of calcium ion transmembrane transporter activity [ISO]
- regulation of calcium ion transport [ISO]
- regulation of cardiac muscle cell contraction [ISO]
- regulation of cardiac muscle cell membrane potential [ISO]
- regulation of cardiac muscle contraction [ISO]
- regulation of cardiac muscle contraction by calcium ion signaling [ISO]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [ISO]
- regulation of cation channel activity [ISO]
- regulation of heart rate [ISO]
- regulation of heart rate by cardiac conduction [ISO]
- regulation of release of sequestered calcium ion into cytosol [ISO]
- regulation of ventricular cardiac muscle cell membrane repolarization [ISO]
- response to methylmercury [IEP]
- ventricular cardiac muscle cell action potential [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- A band [ISO]
- M band [ISO]
- T-tubule [ISO]
- Z disc [ISO]
- basolateral plasma membrane [ISO]
- cell [ISO]
- costamere [ISO]
- cytoplasm [ISO]
- cytoskeleton [IDA]
- integral component of plasma membrane [ISO]
- intercalated disc [ISO]
- intracellular [ISO]
- membrane raft [IDA]
- neuron projection [IDA]
- neuronal postsynaptic density [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [IDA, ISO]
- sarcolemma [ISO]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Plasma membrane-cytoskeleton-endoplasmic reticulum complexes in neurons and astrocytes.
The possibility that certain integral plasma membrane (PM) proteins involved in Ca(2+) homeostasis form junctional units with adjacent endoplasmic reticulum (ER) in neurons and glia was explored using immunoprecipitation and immunocytochemistry. Rat brain membranes were solubilized with the mild, non-ionic detergent, IGEPAL CA-630. Na(+)/Ca(2+) exchanger type 1 (NCX1), a key PM Ca(2+) transporter, was immunoprecipitated from the detergent-soluble fraction. Several ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID