BAIT

JNK-1

CELE_B0478.1
Protein JNK-1
Caenorhabditis elegans
PREY

UNC-25

CELE_Y37D8A.23
Protein UNC-25
GO Process (2)
GO Function (2)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Caenorhabditis elegans

Phenotypic Suppression

A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons.

Kawasaki M, Hisamoto N, Iino Y, Yamamoto M, Ninomiya-Tsuji J, Matsumoto K

The c-Jun N-terminal kinase (JNK) of the MAP kinase superfamily is activated in response to a variety of cellular stresses and is involved in apoptosis in neurons. However, the roles of the JNK signaling pathway in the nervous system are unknown. The genes for the Caenorhabditis elegans homolog of JNK, JNK-1, and its direct activator, JKK-1, were isolated based on ... [more]

EMBO J. Jul. 01, 1999; 18(13);3604-15 [Pubmed: 10393177]

Throughput

  • Low Throughput

Additional Notes

  • jnk1 activated by jkk1

Curated By

  • BioGRID