BAIT
BBS2
BBS
Bardet-Biedl syndrome 2
GO Process (16)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- Golgi to plasma membrane protein transport [IMP]
- adult behavior [ISS]
- brain morphogenesis [ISS]
- cerebral cortex development [ISS]
- cilium morphogenesis [ISS]
- fat cell differentiation [ISS]
- hippocampus development [ISS]
- melanosome transport [ISS]
- negative regulation of appetite by leptin-mediated signaling pathway [ISS]
- negative regulation of multicellular organism growth [ISS]
- photoreceptor cell maintenance [ISS]
- protein localization [ISS]
- protein localization to organelle [ISS]
- regulation of cilium beat frequency involved in ciliary motility [ISS]
- sperm axoneme assembly [ISS]
- striatum development [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
EEF1A1
CCS-3, CCS3, EE1A1, EEF-1, EEF1A, EF-Tu, EF1A, GRAF-1EF, HNGC:16303, LENG7, PTI1, eEF1A-1, RP11-505P4.2
eukaryotic translation elongation factor 1 alpha 1
GO Process (5)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Novel interaction partners of Bardet-Biedl syndrome proteins.
Bardet-Biedl syndrome (BBS) is a rare, developmental disorder characterized by six major symptoms: rod-cone dystrophy, obesity, polydactyly, renal abnormalities, learning difficulties, and hypogonadism. Secondary features include cardiac and hepatic anomalies, metabolic disturbancies, and hearing loss. BBS is genetically heterogeneous with 12 disease genes (BBS1-BBS12) described thus far. Current data suggest a functional disturbance in ciliary function and intraflagellar transport being ... [more]
Cell Motil. Cytoskeleton Feb. 01, 2008; 65(2);143-55 [Pubmed: 18000879]
Throughput
- Low Throughput
Curated By
- BioGRID