BAIT
BBS7
BBS2L1
Bardet-Biedl syndrome 7
GO Process (9)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- cilium morphogenesis [ISS]
- determination of left/right symmetry [ISS]
- digestive tract morphogenesis [ISS]
- fat cell differentiation [ISS]
- heart looping [ISS]
- melanosome transport [ISS]
- pigment granule aggregation in cell center [ISS]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [IPI]
- regulation of transcription from RNA polymerase II promoter [IPI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- BBSome [IDA]
- centrosome [IDA]
Homo sapiens
PREY
PAX2
FSGS7, PAPRS, RP11-179B2.1
paired box 2
GO Process (62)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- axonogenesis [TAS]
- brain morphogenesis [ISS]
- branching involved in ureteric bud morphogenesis [IEP, ISS]
- camera-type eye development [ISS]
- cell fate determination [ISS]
- cellular response to glucose stimulus [ISS]
- cellular response to hydrogen peroxide [ISS]
- cellular response to retinoic acid [ISS]
- cochlea development [ISS]
- cochlea morphogenesis [ISS]
- glial cell differentiation [ISS]
- inner ear morphogenesis [ISS]
- mesenchymal to epithelial transition [ISS]
- mesenchymal to epithelial transition involved in metanephros morphogenesis [ISS]
- mesodermal cell fate specification [ISS]
- mesonephros development [ISS]
- metanephric collecting duct development [ISS]
- metanephric distal convoluted tubule development [ISS]
- metanephric epithelium development [IEP]
- metanephric mesenchymal cell differentiation [ISS]
- metanephric mesenchyme development [ISS]
- metanephric nephron tubule formation [ISS]
- negative regulation of apoptotic process [IDA, IMP]
- negative regulation of apoptotic process involved in metanephric collecting duct development [ISS]
- negative regulation of apoptotic process involved in metanephric nephron tubule development [ISS]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- negative regulation of cytolysis [IMP]
- negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis [ISS]
- negative regulation of mesenchymal cell apoptotic process involved in metanephros development [ISS]
- negative regulation of programmed cell death [ISS]
- negative regulation of reactive oxygen species metabolic process [IDA]
- negative regulation of transcription, DNA-templated [IMP]
- nephric duct formation [ISS]
- neural tube closure [ISS]
- optic chiasma development [ISS]
- optic cup morphogenesis involved in camera-type eye development [ISS]
- optic nerve development [ISS]
- optic nerve morphogenesis [ISS]
- optic nerve structural organization [ISS]
- positive regulation of branching involved in ureteric bud morphogenesis [ISS]
- positive regulation of epithelial cell proliferation [IDA]
- positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [ISS]
- positive regulation of metanephric DCT cell differentiation [ISS]
- positive regulation of metanephric glomerulus development [ISS]
- positive regulation of optic nerve formation [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISS]
- positive regulation of transcription, DNA-templated [IDA]
- pronephric field specification [ISS]
- pronephros development [ISS]
- protein kinase B signaling [ISS]
- reactive oxygen species metabolic process [ISS]
- regulation of metanephric nephron tubule epithelial cell differentiation [ISS]
- regulation of metanephros size [IMP]
- retinal pigment epithelium development [ISS]
- stem cell differentiation [ISS]
- transcription from RNA polymerase II promoter [TAS]
- transcription, DNA-templated [ISS]
- ureter development [ISS]
- ureter maturation [ISS]
- urogenital system development [ISS]
- vestibulocochlear nerve formation [ISS]
- visual perception [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Novel interaction partners of Bardet-Biedl syndrome proteins.
Bardet-Biedl syndrome (BBS) is a rare, developmental disorder characterized by six major symptoms: rod-cone dystrophy, obesity, polydactyly, renal abnormalities, learning difficulties, and hypogonadism. Secondary features include cardiac and hepatic anomalies, metabolic disturbancies, and hearing loss. BBS is genetically heterogeneous with 12 disease genes (BBS1-BBS12) described thus far. Current data suggest a functional disturbance in ciliary function and intraflagellar transport being ... [more]
Cell Motil. Cytoskeleton Feb. 01, 2008; 65(2);143-55 [Pubmed: 18000879]
Throughput
- Low Throughput
Curated By
- BioGRID