BAIT
XPO1
CRM1, emb, exp1
exportin 1
GO Process (12)
GO Function (3)
GO Component (11)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- gene expression [TAS]
- intracellular transport of virus [TAS]
- mRNA metabolic process [TAS]
- mitotic cell cycle [TAS]
- negative regulation of transforming growth factor beta receptor signaling pathway [TAS]
- protein export from nucleus [IMP]
- ribosomal large subunit export from nucleus [IMP]
- ribosomal small subunit export from nucleus [IMP]
- transforming growth factor beta receptor signaling pathway [TAS]
- viral life cycle [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MAPKAPK2
AA960234, MAPKAP-K2, MK-2, MK2, Rps6kc1
MAP kinase-activated protein kinase 2
GO Process (17)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- 3'-UTR-mediated mRNA stabilization [ISO]
- G2 DNA damage checkpoint [ISO]
- cellular response to DNA damage stimulus [ISO]
- cellular response to vascular endothelial growth factor stimulus [ISO]
- inflammatory response [IMP]
- inner ear development [IDA]
- mRNA stabilization [IMP]
- macropinocytosis [IMP]
- peptidyl-serine phosphorylation [ISO]
- protein phosphorylation [IDA]
- regulation of interleukin-6 production [IMP]
- regulation of tumor necrosis factor production [IMP, ISO]
- response to cytokine [ISO]
- response to lipopolysaccharide [IMP]
- response to stress [ISO]
- toll-like receptor signaling pathway [IMP]
- vascular endothelial growth factor receptor signaling pathway [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Sequence and structural analyses of nuclear export signals in the NESdb database.
We compiled >200 nuclear export signal (NES)-containing CRM1 cargoes in a database named NESdb. We analyzed the sequences and three-dimensional structures of natural, experimentally identified NESs and of false-positive NESs that were generated from the database in order to identify properties that might distinguish the two groups of sequences. Analyses of amino acid frequencies, sequence logos, and agreement with existing ... [more]
Mol. Biol. Cell Sep. 01, 2012; 23(18);3677-93 [Pubmed: 22833565]
Throughput
- Low Throughput
Curated By
- BioGRID