BAIT
XPO1
CRM1, emb, exp1
exportin 1
GO Process (12)
GO Function (3)
GO Component (11)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- gene expression [TAS]
- intracellular transport of virus [TAS]
- mRNA metabolic process [TAS]
- mitotic cell cycle [TAS]
- negative regulation of transforming growth factor beta receptor signaling pathway [TAS]
- protein export from nucleus [IMP]
- ribosomal large subunit export from nucleus [IMP]
- ribosomal small subunit export from nucleus [IMP]
- transforming growth factor beta receptor signaling pathway [TAS]
- viral life cycle [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PLCD1
Plc1
phospholipase C, delta 1
GO Process (15)
GO Function (10)
GO Component (7)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IDA]
- angiogenesis [ISO]
- cytosolic calcium ion homeostasis [IMP]
- labyrinthine layer blood vessel development [ISO]
- positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway [IMP]
- positive regulation of inositol trisphosphate biosynthetic process [IMP]
- positive regulation of norepinephrine secretion [IMP]
- regulation of cell proliferation [ISO]
- regulation of phospholipase C activity [IMP]
- response to aluminum ion [IEP]
- response to calcium ion [IMP]
- response to hyperoxia [IEP]
- response to organonitrogen compound [IEP]
- response to peptide hormone [IMP]
- response to prostaglandin F [IEP]
Gene Ontology Molecular Function- GTPase activating protein binding [ISO]
- calcium ion binding [IDA]
- phosphatidic acid binding [ISO]
- phosphatidylinositol phosphate binding [ISO]
- phosphatidylinositol phospholipase C activity [IDA]
- phosphatidylinositol-4,5-bisphosphate binding [IDA]
- phosphatidylserine binding [ISO]
- phospholipase C activity [ISO]
- phospholipid binding [IDA]
- protein binding [IPI]
- GTPase activating protein binding [ISO]
- calcium ion binding [IDA]
- phosphatidic acid binding [ISO]
- phosphatidylinositol phosphate binding [ISO]
- phosphatidylinositol phospholipase C activity [IDA]
- phosphatidylinositol-4,5-bisphosphate binding [IDA]
- phosphatidylserine binding [ISO]
- phospholipase C activity [ISO]
- phospholipid binding [IDA]
- protein binding [IPI]
Gene Ontology Cellular Component
Rattus norvegicus
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Sequence and structural analyses of nuclear export signals in the NESdb database.
We compiled >200 nuclear export signal (NES)-containing CRM1 cargoes in a database named NESdb. We analyzed the sequences and three-dimensional structures of natural, experimentally identified NESs and of false-positive NESs that were generated from the database in order to identify properties that might distinguish the two groups of sequences. Analyses of amino acid frequencies, sequence logos, and agreement with existing ... [more]
Mol. Biol. Cell Sep. 01, 2012; 23(18);3677-93 [Pubmed: 22833565]
Throughput
- Low Throughput
Curated By
- BioGRID