BAIT
SNTA1
LQT12, SNT1, TACIP1, dJ1187J4.5
syntrophin, alpha 1
GO Process (6)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
HTR2B
5-HT(2B), 5-HT2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
GO Process (35)
GO Function (5)
GO Component (2)
Gene Ontology Biological Process
- ERK1 and ERK2 cascade [IMP]
- G-protein coupled receptor signaling pathway [IMP]
- activation of phospholipase C activity [IDA]
- cGMP biosynthetic process [IDA]
- calcium-mediated signaling [IMP]
- cardiac muscle hypertrophy [ISS]
- cellular calcium ion homeostasis [IDA]
- cellular response to temperature stimulus [ISS]
- embryonic morphogenesis [ISS]
- heart morphogenesis [ISS]
- intestine smooth muscle contraction [IMP]
- negative regulation of apoptotic process [ISS]
- negative regulation of autophagy [IMP]
- negative regulation of cell death [IMP]
- neural crest cell differentiation [ISS]
- neural crest cell migration [ISS]
- phosphatidylinositol 3-kinase signaling [IDA]
- phosphorylation [IMP]
- positive regulation of ERK1 and ERK2 cascade [IDA]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IEP]
- positive regulation of MAP kinase activity [IDA]
- positive regulation of cell division [ISS]
- positive regulation of cell proliferation [IDA, IMP]
- positive regulation of cytokine production [IDA]
- positive regulation of cytokine secretion [ISS]
- positive regulation of endothelial cell proliferation [IMP]
- positive regulation of nitric-oxide synthase activity [IDA]
- positive regulation of phosphatidylinositol biosynthetic process [IDA]
- protein kinase C signaling [IMP]
- protein kinase C-activating G-protein coupled receptor signaling pathway [ISS]
- regulation of behavior [IMP]
- release of sequestered calcium ion into cytosol [IDA, IMP]
- response to drug [IDA]
- serotonin receptor signaling pathway [IMP]
- vasoconstriction [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.
SPOT synthesis permits parallel synthesis and screening of thousands of cellulose membrane-bound peptides to study protein-protein interactions in a proteomic context. Recognition of C-terminal residues is one of the most common binding features of PDZ domains. Unfortunately, most solid support-bound peptide libraries lack a free C terminus due to C-terminal fixation on the solid support. To overcome this restriction, we ... [more]
Chem. Biol. Apr. 01, 2004; 11(4);449-59 [Pubmed: 15123239]
Throughput
- Low Throughput
Curated By
- BioGRID