BAIT

MPG

AAG, ADPG, APNG, CRA36.1, MDG, Mid1, PIG11, PIG16, anpg, Z69720.1-002
N-methylpurine-DNA glycosylase
GO Process (5)
GO Function (3)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

FXR2

FMR1L2, FXR2P
fragile X mental retardation, autosomal homolog 2
GO Process (1)
GO Function (5)
GO Component (6)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins.

Liang C, Zhang X, Song S, Tian C, Yin Y, Xing G, He F, Zhang L

N-methylpurine DNA glycosylase (MPG), a DNA repair enzyme, functions in the DNA base excision repair (BER) pathway. Aberrant over-expression of MPG in various cancers suggests an important role of MPG in carcinogenesis. Identification of MPG-interacting proteins will help to dissect the molecular link between MPG and cancer development. In the present study, using immunoprecipitation coupled with mass spectrometry (IP/MS), we ... [more]

Biochem. Biophys. Res. Commun. Apr. 19, 2013; 433(4);415-9 [Pubmed: 23537643]

Throughput

  • Low Throughput

Curated By

  • BioGRID