BAIT
MPG
AAG, ADPG, APNG, CRA36.1, MDG, Mid1, PIG11, PIG16, anpg, Z69720.1-002
N-methylpurine-DNA glycosylase
GO Process (5)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GSN
ADF, AGEL, RP11-477J21.1
gelsolin
GO Process (6)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins.
N-methylpurine DNA glycosylase (MPG), a DNA repair enzyme, functions in the DNA base excision repair (BER) pathway. Aberrant over-expression of MPG in various cancers suggests an important role of MPG in carcinogenesis. Identification of MPG-interacting proteins will help to dissect the molecular link between MPG and cancer development. In the present study, using immunoprecipitation coupled with mass spectrometry (IP/MS), we ... [more]
Biochem. Biophys. Res. Commun. Apr. 19, 2013; 433(4);415-9 [Pubmed: 23537643]
Throughput
- Low Throughput
Curated By
- BioGRID