SMARCD3
Gene Ontology Biological Process
- cellular lipid metabolic process [TAS]
- chromatin remodeling [IC, IDA]
- neural retina development [IEP]
- nucleosome disassembly [IDA]
- positive regulation of neuroblast proliferation [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- regulation of transcription from RNA polymerase II promoter [IMP, NAS]
- small molecule metabolic process [TAS]
- transcription, DNA-templated [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ESRRA
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit.
Transcriptional activity relies on coregulators that modify chromatin structure or serve as bridging factors between transcription factors and the basal transcription machinery. We identified a new coregulator of peroxisome proliferator-activated receptor gamma, BRG1/Brm-associated factor of 60 kDa, subunit c2 (BAF60c2), in a yeast two-hybrid screen of a human adipose tissue cDNA library. BAF60c2 represents a new isoform of BAF60c, a ... [more]
Throughput
- Low Throughput
Additional Notes
- Interaction is independent of ligand, 17beta-estradiol (Chebi: unknown)
- Isoform: Q6STE5-1 interacts with P11474
- Isoform: Q6STE5-2 interacts with P11474
Curated By
- BioGRID