PREY

CMYA5

2310076E16Rik, 2310076E21Rik, AA420382, AI504003, Srfsd, Tims, sr553
cardiomyopathy associated 5
GO Process (3)
GO Function (2)
GO Component (1)
Mus musculus

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

Myospryn is a novel binding partner for dysbindin in muscle.

Benson MA, Tinsley CL, Blake DJ

Dysbindin is a coiled-coil-containing protein that was initially identified in a screen for dystrobrevin-interacting proteins. Recently, dysbindin has been shown to be involved in the biogenesis of lysosome-related organelles and is also a major schizophrenia susceptibility factor. Although dysbindin has been implicated in a number of different cellular processes, little is known about its function. To determine the function of ... [more]

J. Biol. Chem. Mar. 12, 2004; 279(11);10450-8 [Pubmed: 14688250]

Throughput

  • Low Throughput

Curated By

  • BioGRID